SCHEMBL2273385

SCHEMBL2273385

CCCC[Si](C)(CCCC)N(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8319015 0.90 DNM1 (0.39) DNM1TSHRLMNATHRB
SCHEMBL2269625 0.89 DNM1 (0.31) DNM1TSHRLMNA
SCHEMBL8178948 0.87 DNM1 (0.40) DNM1TSHRLMNATHRB
SCHEMBL8193626 0.87 DNM1 (0.40) DNM1TSHRLMNATHRB
SCHEMBL8319455 0.87 DNM1 (0.40) DNM1TSHRLMNATHRB
SCHEMBL8318977 0.79 DNM1 (0.34) DNM1TSHRTHRB
SCHEMBL2102668 0.77 DNM1 (0.33) DNM1TSHRLMNATHRB
SCHEMBL422241 0.77 DNM1 (0.33) DNM1TSHRLMNATHRB
SCHEMBL2271868 0.74 TSHR (0.32) TSHRLMNATHRB
SCHEMBL328755 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-7795368-B2 Silicon- and polysilyl cyamelurates as well as -cyanurates, methods for the production thereof and their use ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. (DE) 2010-09-14 US disclosed
US-20080262185-A1 Silicon- and Polysilyl Cyamelurates as Well as -Cyanurates, Methods for the Production Thereof and Their Use ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. (DE) 2008-10-23 US disclosed