Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319455 | 0.91 | DNM1 (0.40) | DNM1TSHRTHRBKCNH2 | |
| SCHEMBL8319015 | 0.89 | DNM1 (0.39) | DNM1TSHRTHRBKCNH2 | |
| SCHEMBL8178948 | 0.87 | DNM1 (0.40) | DNM1TSHRTHRBKCNH2 | |
| SCHEMBL8193626 | 0.87 | DNM1 (0.40) | DNM1TSHRTHRBKCNH2 | |
| SCHEMBL258804 | 0.84 | TSHR (0.42) | DNM1TSHRTHRB | |
| SCHEMBL7922841 | 0.84 | TSHR (0.42) | DNM1TSHRTHRB | |
| SCHEMBL30238622 | 0.84 | TSHR (0.42) | DNM1TSHRTHRB | |
| SCHEMBL422635 | 0.84 | TSHR (0.42) | DNM1TSHRTHRB | |
| SCHEMBL11969287 | 0.84 | TSHR (0.42) | DNM1TSHRTHRB | |
| SCHEMBL30239111 | 0.84 | TSHR (0.42) | DNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869724-A | REAGENTS FOR MODIFYING THE SURFACE OF LIQUID CHROMATOGRAPHY SUPPORTS | HEWLETT-PACKARD COMPANY (US) | 1999-02-09 | — | — | US | disclosed |