SCHEMBL2273458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2273879	0.87	CACNB4 (0.43)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL2272549	0.87	CACNB4 (0.43)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL2270997	0.87	PDE4B (0.48)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL2275569	0.86	RBP4 (0.47)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL2277079	0.84	AR (0.47)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL2278755	0.81	USP30 (0.48)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL2273699	0.81	NEK2 (0.41)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL15058234	0.80	RBP4 (0.45)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL15058534	0.79	USP30 (0.46)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F
	SCHEMBL3957421	0.79	RBP4 (0.56)	CACNB4CACNA1ACACNA1GCACNG3CACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.