SCHEMBL22734597

SCHEMBL22734597

CC(NS(=O)(=O)c1ccc(Cl)c2nonc12)N(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 1/20 0.46
RORC P51449 1/20 0.46
NR1H2 P55055 1/20 0.46
NLRP3 Q96P20 2/20 0.42
PFKFB3 Q16875 1/20 0.41
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 2/20 0.33
APAF1 O14727 1/20 0.33
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
CASP6 P55212 1/20 0.33
SAE1 Q9UBE0 1/20 0.33
UBA2 Q9UBT2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL22734514 0.86 RORA (0.46) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL22734625 0.84 KMT2A (0.38) RORARORCNR1H2NLRP3KMT2A
SCHEMBL22734676 0.81 ALDH1A1 (0.37) NLRP3KMT2AALDH1A1MAPTCASP6
SCHEMBL22734551 0.81 NLRP3 (0.34) NLRP3KMT2AALDH1A1NR3C1RAB9A
SCHEMBL4946887 0.81 RORA (0.46) RORARORCNR1H2NLRP3PFKFB3
Hydrochloric Acid SCHEMBL22734516 0.80 RORA (0.45) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL3498898 0.78 RORA (0.52) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL3501251 0.75 HDAC3 (0.45) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL15926056 0.75 GAA (0.49) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL19391630 0.73 RORA (0.46) RORARORCNR1H2NLRP3PFKFB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240329051-A1 PEPTIDE ANALYSIS METHOD AND PEPTIDE ANALYSIS APPARATUS SHIMADZU CORPORATION (JP) 2024-10-03 US disclosed
WO-2023013047-A1 PEPTIDE ANALYSIS METHOD AND PEPTIDE ANALYSIS APPARATUS 株式会社島津製作所 2023-02-09 WO disclosed
US-20200386767-A1 Analytical method and apparatus using fingerprints on the basis of types in expression levels of express trace proteins and/or peptides contained in living tissue and/or biological fluid SHINWA CHEMICAL INDUSTRIES LTD. (JP) 2020-12-10 US disclosed