SCHEMBL227358

SCHEMBL227358

C=C(C)C(=O)OCO[Si](C)(C)OC

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.42
THRB P10828 1/20 0.40
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17886093 0.90 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL1232370 0.85 TSHR (0.42) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL2859776 0.82 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL27680823 0.80 THRB (0.41) TSHRALDH1A1THRB
SCHEMBL27707261 0.79 ALDH1A1 (0.39) TSHRALDH1A1
SCHEMBL27825885 0.78 TSHR (0.44) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL4649747 0.78 THRB (0.42) TSHRALDH1A1THRB
SCHEMBL455671 0.78 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL27680092 0.77 THRB (0.44) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL148579 0.76 TSHR (0.58) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698580-A1 CROSSLINKABLE COMPOSITIONS BASED ON SILANE-CROSSLINKING ORGANIC POLYMERS WITH HIGH THERMAL CONDUCTIVITY Wacker Chemie AG (DE) 2026-02-25 EP disclosed
WO-2025223681-A1 CROSS-LINKABLE COMPOSITIONS ON THE BASIS OF ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2025-10-30 WO disclosed
EP-4499747-A1 CROSS-LINKABLE COMPOSITIONS ON THE BASIS OF ORGANOSILICON COMPOUNDS Wacker Chemie AG (DE) 2025-02-05 EP disclosed
WO-2024217693-A1 CROSSLINKABLE COMPOSITIONS BASED ON SILANE-CROSSLINKING ORGANIC POLYMERS WITH HIGH THERMAL CONDUCTIVITY WACKER CHEMIE AG (DE) 2024-10-24 WO disclosed
WO-2023186261-A1 CROSS-LINKABLE COMPOSITIONS ON THE BASIS OF ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2023-10-05 WO disclosed
EP-4208492-A1 CROSS-LINKABLE SUBSTANCES BASED ON ORGANYLOXYSILANE-TERMINATED POLYMERS Wacker Chemie AG (DE) 2023-07-12 EP disclosed
EP-2949717-B1 ADHESIVE COMPOSITION, ADHESIVE FILM, AND METHOD FOR PREPARING ORGANIC ELECTRONIC DEVICE BY USING SAME LG CHEMICAL LTD (KR) 2022-04-27 EP disclosed
EP-3924428-A1 MULTI-COMPONENT CROSSLINKABLE MASSES BASED ON ORGANYLOXYSILANE-TERMINATED POLYMERS Wacker Chemie AG (DE) 2021-12-22 EP disclosed
EP-2966139-B1 ADHESIVE COMPOSITION, ADHESIVE FILM, AND METHOD FOR MANUFACTURING ORGANIC ELECTRONIC DEVICE USING SAME LG CHEMICAL LTD (KR) 2021-09-29 EP disclosed
EP-2966138-B1 ADHESIVE COMPOSITION, ADHESIVE FILM, AND METHOD FOR MANUFACTURING ORGANIC ELECTRONIC DEVICE USING SAME LG CHEMICAL LTD (KR) 2021-07-14 EP disclosed
CN-103748128-A Cross-linkable materials based on organyl oxysilane-terminated polymers WACKER CHEMIE AG 2014-04-23 CN disclosed
CN-103649150-A Polyurea coatings containing silane PPG IND OHIO INC 2014-03-19 CN disclosed
WO-2014026906-A1 MULTICOMPONENT CROSSLINKABLE COMPOSITIONS BASED ON ORGANYLOXYSILANE-TERMINATED POLYMERS WACKER CHEMIE AG (DE) 2014-02-20 WO disclosed
WO-2013174708-A1 CROSSLINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2013-11-28 WO disclosed
WO-2013143905-A1 CROSSLINKABLE COMPOSITIONS BASED ON ORGANYLOXYSILANE-TERMINATED POLYMERS WACKER CHEMIE AG (DE) 2013-10-03 WO disclosed
WO-2013079330-A2 CROSS-LINKABLE MASSES BASED ON ORGANYL-OXYSILANE-TERMINATED POLYURETHANES WACKER CHEMIE AG (DE) 2013-06-06 WO disclosed
CN-102634025-A Aqueous silane systems based on bis(trialkoxysilylalkyl)amines EVONIK DEGUSSA GMBH 2012-08-15 CN disclosed
CN-101376710-B Aqueous silane systems based on bis (trialkoxysilylalkyl) amines EVONIK DEGUSSA GMBH 2012-08-08 CN disclosed
US-20120004437-A1 METHOD FOR PRODUCING (METH)ACRYLOSILANES WACKER CHEMIE AG (DE) 2012-01-05 US disclosed
CN-101376710-A Aqueous silane systems based on bis (trialkoxysilylalkyl) amines EVONIK DEGUSSA GMBH (DE) 2009-03-04 CN disclosed