SCHEMBL2859776

SCHEMBL2859776

C=C(C)C(=O)OCO[Si](C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ALDH1A1 P00352 2/20 0.46
THRB P10828 1/20 0.44
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17886093 0.87 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL27825885 0.83 TSHR (0.44) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL227358 0.82 TSHR (0.42) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL27680092 0.82 THRB (0.44) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL1232370 0.82 TSHR (0.42) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL148579 0.81 TSHR (0.58) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL679847 0.81 THRB (0.57) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL3797198 0.79 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL545330 0.79 THRB (0.39) TSHRALDH1A1THRB
Hydrochloric Acid SCHEMBL14976774 0.79 TSHR (0.56) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180115006-A1 POLYMER ELECTROLYTE, METHOD OF PREPARING THE POLYMER ELECTROLYTE, AND LITHIUM METAL BATTERY INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-04-26 US disclosed
US-7843625-B2 Sheet for electrophoretic display devices, process for its production, and its applications SEIKO EPSON CORPORATION (JP) 2010-11-30 US disclosed
US-20090059349-A1 Sheet for electrophoretic display devices, process for its production, and its applications SEIKO EPSON CORPORATION (JP) 2009-03-05 US disclosed
US-20070160561-A1 AMPHIPHILIC STAR BLOCK COPOLYMERS FIRMENICH SA (CH) 2007-07-12 US disclosed
CN-1262582-C Cured coatings having improved scratch resistance, coated substrates and methods related thereto PPG IND OHIO INC (US) 2006-07-05 CN disclosed
CN-1261508-C Coating compositions having improved scratch resistance, coated substrates and methods related thereto PPG IND OHIO INC (US) 2006-06-28 CN disclosed
CN-1209427-C Coating compositions having improved scratch resistance, coated substrates, and methods related thereto PPG IND OHIO INC (US) 2005-07-06 CN disclosed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US disclosed
CN-1454243-A Dual cure coating compositions having improved scratch resistance, coated substrates and methods related thereto PPG IND OHIO INC (US) 2003-11-05 CN disclosed
CN-1377392-A Flexible coating compositions having improved scratch resistance, coated substrates and methods related thereto PPG IND OHIO INC (US) 2002-10-30 CN disclosed
CN-1376175-A Cured coatings having improved scratch resistance, coated substrates and methods related thereto PPG IND OHIO INC (US) 2002-10-23 CN disclosed
CN-1376187-A Coating compositions having improved scratch resistance, coated substrates and methods related thereto PPG IND OHIO INC (US) 2002-10-23 CN disclosed
CN-1376186-A Coating compositions having improved scratch resistance, coated substrates and methods related thereto PPG IND OHIO INC (US) 2002-10-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885THRB 4533/4885
US-20070160561-A1 AMPHIPHILIC STAR BLOCK COPOLYMERS ABCB4, ABCB7, ABCC5 TSHR 1732/4885ALDH1A1 3042/4885THRB 422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.