Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14729359 | 0.86 | FOLH1 (0.63) | FOLH1 | |
| SCHEMBL14729355 | 0.81 | FOLH1 (0.57) | FOLH1 | |
| SCHEMBL12264736 | 0.75 | DGAT1 (0.38) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL12264732 | 0.73 | LMNA (0.42) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL941529 | 0.73 | LMNA (0.46) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL12427908 | 0.73 | TYMP (0.44) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL20341420 | 0.73 | FOLH1 (0.71) | FOLH1 | |
| SCHEMBL25211225 | 0.71 | CA12 (0.49) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL28356435 | 0.71 | CA12 (0.49) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL28352617 | 0.71 | CA12 (0.49) | LMNATHRBCYP2C19CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210032286-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2021-02-04 | — | — | US | disclosed |
| US-20210024574-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2021-01-28 | — | — | US | disclosed |
| US-10894807-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2021-01-19 | — | — | US | disclosed |
| US-20200377549-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894807-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | LMNA 3855/4885THRB 2500/4885CYP2C19 4734/4885 |
| US-20200377549-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | LMNA 3855/4885THRB 2500/4885CYP2C19 4734/4885 |
| US-20210032286-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | LMNA 3855/4885THRB 2500/4885CYP2C19 4734/4885 |
| US-20210024574-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | LMNA 3855/4885THRB 2500/4885CYP2C19 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.