SCHEMBL2273757

SCHEMBL2273757

CN(C)[SiH2]C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30937812 0.75
SCHEMBL4580357 0.65
SCHEMBL6347659 0.65
SCHEMBL2530385 0.58
SCHEMBL15343549 0.58
SCHEMBL27750233 0.55
SCHEMBL10289416 0.55
Trimethylammonium SCHEMBL2701069 0.55
SCHEMBL17045940 0.51
SCHEMBL968099 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2592075-B1 PYRIDAZINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES UNIV NORTHWESTERN (US) 2015-04-29 EP claimed
EP-0793668-B1 DERIVATIVES OF CARBOHYDRATES AND COMPOSITIONS CONTAINING THEM BIONERIS AB (SE) 2004-03-31 EP claimed
US-9527819-B2 Pyridazine compounds, compositions and methods NORTHWESTERN UNIVERSITY 2016-12-27 US disclosed
US-20150175555-A1 PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS NORTHWESTERN UNIVERSITY (US) 2015-06-25 US disclosed
CN-102892765-B Cyclohexylamine derivatives having beta 2 adrenergic agonist and M3 muscarinic antagonist activity ALMIRALL SA 2015-04-29 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
CN-102892765-A Novel cyclohexylamine derivatives having beta 2 adrenergic agonist and M3 muscarinic antagonist activity ALMIRALL SA 2013-01-23 CN disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
EP-2148667-A1 USE OF CYCLOHEXANEHEXOL DERIVATIVES IN THE TREATMENT OF OCULAR DISEASES Waratah Pharmaceuticals, Inc. (CA) 2010-02-03 EP disclosed
WO-2008131481-A1 TREATMENT OF MESANGIOPROLIFERATIVE DISEASES FIBROTECH THERAPEUTICS PTY LTD (AU) 2008-11-06 WO disclosed
WO-2008124930-A1 USE OF CYCLOHEXANEHEXOL DERIVATIVES FOR THE TREATMENT OF POLYGLUTAMINE DISEASES MCLAURIN JOANNE (CA) 2008-10-23 WO disclosed
EP-1022619-B1 Toner and image forming method CANON KK (JP) 2006-07-26 EP disclosed
EP-0759439-B1 Synthesis of silylated cyanohydrins CREANOVA INC (US) 2002-09-18 EP disclosed
EP-0713153-B1 Toner for developing electrostatic images, two component type developer, developing method, image forming method, heat fixing method, and process for producing toner CANON KK (JP) 2001-03-14 EP disclosed
US-6156471-A Toner and image forming method CANON KABUSHIKI KAISHA (JP) 2000-12-05 US disclosed
EP-1022619-A1 Toner and image forming method CANON KABUSHIKI KAISHA (JP) 2000-07-26 EP disclosed
US-5824442-A CONTROLLING DEVELOPMENT AND DEVELOPMENT FOR ELECTROSTATIC IMAGES WITH THIN FILMS CANON KABUSHIKI KAISHA (JP) 1998-10-20 US disclosed
US-5707770-A TITANIA OR ALUMINA PARTICLES SURFACE TREATED WITH A SILICON COMPOUND OR SILICONE OIL, IMPROVED PERFORMANCE IN HIGH HUMIDITY CANON KABUSHIKI KAISHA (JP) 1998-01-13 US disclosed
EP-0759439-A2 Synthesis of silylated cyanohydrins HÜLS AMERICA INC. (US) 1997-02-26 EP disclosed
EP-0713153-A2 Toner for developing electrostatic images, two component type developer, developing method, image forming method, heat fixing method, and process for producing toner CANON KABUSHIKI KAISHA (JP) 1996-05-22 EP disclosed