SCHEMBL2273783

SCHEMBL2273783

CC[SiH](CNC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HRH1 P35367 2/20 0.38
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
TAAR1 Q96RJ0 4/20 0.36
HTR1B P28222 2/20 0.36
HTR1D P28221 1/20 0.36
ATM Q13315 1/20 0.35
SIGMAR1 Q99720 3/20 0.33
SLC18A2 Q05940 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80927 0.81 TP53 (0.41) HTR2AHRH1TAAR1SIGMAR1MEN1
SCHEMBL2272352 0.81 HTT (0.37) SIGMAR1MEN1KMT2ATP53TSHR
Water SCHEMBL20720558 0.79 TP53 (0.39) HTR2AHRH1KDM4ECYP3A4MAPT
Fluoride SCHEMBL27660896 0.79 TP53 (0.39) HTR2AHRH1TAAR1SIGMAR1MEN1
SCHEMBL29847552 0.73 TP53 (0.35) SIGMAR1TP53LMNA
SCHEMBL27669962 0.73 TAAR1 (0.38) HTR2AHRH1TAAR1SIGMAR1TP53
SCHEMBL2273902 0.73 TP53 (0.35) TP53LMNA
SCHEMBL2102293 0.71 KDM4E (0.38) HTR2AHRH1KDM4ECYP3A4MAPT
SCHEMBL10020512 0.71 TP53 (0.33) TP53LMNA
SCHEMBL16395648 0.71 TAAR1 (0.33) TAAR1SIGMAR1SLC18A2L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed