Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27431233 | 0.85 | MAOA (0.43) | MAOAMAPTALDH1A1HPGDBCHE | |
| SCHEMBL10621158 | 0.83 | ALDH1A1 (0.57) | MAOAMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL10621154 | 0.83 | ALDH1A1 (0.57) | MAOAMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL627482 | 0.78 | MAOA (0.58) | MAOAMAPTALDH1A1HPGDBCHE | |
| SCHEMBL30184394 | 0.78 | MAOA (0.58) | MAOAMAPTALDH1A1HPGDBCHE | |
| SCHEMBL8711321 | 0.72 | BCHE (0.41) | MAOAMAPTALDH1A1BCHESMN1; SMN2 | |
| SCHEMBL15893985 | 0.72 | MAOA (0.45) | MAOAMAPTALDH1A1HPGDBCHE | |
| SCHEMBL22739037 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EMEN1KMT2AHTT | |
| SCHEMBL11983361 | 0.71 | PDF (0.63) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL25909343 | 0.71 | MAPT (0.50) | MAPTALDH1A1HPGDBCHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018315-B2 | Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-06-25 | — | — | US | disclosed |
| US-20230242969-A1 | PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPLING AND DETECTION OF INTERSTITIAL FLUID NUCLEIC ACIDS | HOWARD HUGHES MEDICAL INSTITUTE | 2023-08-03 | — | — | US | disclosed |
| US-20230242969-A1 | PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPLING AND DETECTION OF INTERSTITIAL FLUID NUCLEIC ACIDS | HOWARD HUGHES MEDICAL INSTITUTE | 2023-08-03 | — | — | US | disclosed |
| US-20200377929-A1 | PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPLING AND DETECTION OF INTERSTITIAL FLUID NUCLEIC ACIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-12-03 | — | — | US | disclosed |