SCHEMBL22744271

SCHEMBL22744271

CC1CNCc2ncc3ccccc3c2O1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
GPR3 P46089 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
HPGD P15428 2/20 0.32
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HSD17B10 Q99714 2/20 0.31
MAPK1 P28482 1/20 0.31
PARP1 P09874 1/20 0.31
PRKCI P41743 1/20 0.31
PDE4B Q07343 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 2/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24650207 0.83 CYP1A2 (0.36) KDM4EGPR3HPGDLMNA
SCHEMBL24650613 0.83 CYP1A2 (0.36) KDM4EGPR3HPGDLMNA
SCHEMBL22744293 0.83 CYP1A2 (0.36) KDM4EGPR3HPGDLMNA
Hydrochloric Acid SCHEMBL29442631 0.82 CYP1A2 (0.36) KDM4EGPR3TAAR1HPGDLMNA
Hydrochloric Acid SCHEMBL29442749 0.82 CYP1A2 (0.36) KDM4EGPR3TAAR1HPGDLMNA
SCHEMBL8274129 0.66 KDM4E (0.41) KDM4EGPR3ALDH1A1HSD17B10MAPK1
SCHEMBL22798586 0.64 KDM4E (0.39) KDM4EGPR3TAAR1HPGDALDH1A1
SCHEMBL29548484 0.64 KDM4E (0.39) KDM4EGPR3TAAR1HPGDALDH1A1
SCHEMBL22355519 0.63 NTRK1 (0.35) BRD4CREBBP
SCHEMBL22355454 0.63 NTRK1 (0.35) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020241853-A1 BENZOTRIAZOLE DERIVATIVE 宇部興産株式会社 2020-12-03 WO disclosed