Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.31 |
| ▸ | RELA | Q04206 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650207 | 1.00 | CYP1A2 (0.36) | CYP1A2CYP2D6ALPGCYP2C19SMN1; SMN2 | |
| SCHEMBL22744293 | 1.00 | CYP1A2 (0.36) | CYP1A2CYP2D6ALPGCYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29442749 | 0.99 | CYP1A2 (0.36) | CYP1A2CYP2D6ALPGCYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29442631 | 0.99 | CYP1A2 (0.36) | CYP1A2CYP2D6ALPGCYP2C19SMN1; SMN2 | |
| SCHEMBL22744271 | 0.83 | KDM4E (0.33) | KDM4EGPR3LMNAHPGD | |
| SCHEMBL24650471 | 0.77 | NFKB1 (0.45) | CYP1A2CYP2D6ALPGCYP2C19SMN1; SMN2 | |
| SCHEMBL29442713 | 0.77 | NFKB1 (0.45) | CYP1A2CYP2D6ALPGCYP2C19SMN1; SMN2 | |
| SCHEMBL24650011 | 0.74 | CYP1A2 (0.36) | CYP1A2CYP2D6ALPGCYP2C19SMN1; SMN2 | |
| SCHEMBL29442644 | 0.74 | CYP1A2 (0.36) | CYP1A2CYP2D6ALPGCYP2C19SMN1; SMN2 | |
| SCHEMBL24650610 | 0.74 | CYP1A2 (0.34) | CYP1A2KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | KEAP1, NFE2L2, BACH1 | CYP1A2 622/4885CYP2D6 1142/4885ALPG 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.