Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | PRKCI | P41743 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798586 | 1.00 | KDM4E (0.39) | KDM4EGPR3KMT2ALMNAMAPKAPK2 | |
| SCHEMBL10923189 | 0.77 | TP53 (0.39) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL12527287 | 0.66 | GPR3 (0.41) | KDM4EGPR3KMT2ALMNACYP2A6 | |
| SCHEMBL22744271 | 0.64 | KDM4E (0.33) | KDM4EGPR3KMT2ALMNAALDH1A1 | |
| SCHEMBL12962903 | 0.64 | KDM4E (0.36) | KDM4EGPR3ALDH1A1MAPK1PRKCI | |
| SCHEMBL7914307 | 0.63 | CA1 (0.36) | — | |
| SCHEMBL12490689 | 0.63 | KDM4E (0.42) | KDM4EGPR3KMT2ALMNAMAPKAPK2 | |
| SCHEMBL13199592 | 0.63 | CA1 (0.36) | — | |
| SCHEMBL20465820 | 0.62 | KDM4E (0.38) | KDM4EGPR3KMT2ALMNACYP2A6 | |
| SCHEMBL18959589 | 0.62 | KDM4E (0.38) | KDM4EGPR3KMT2ALMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986865-A1 | NEW TRICYCLIC 5-HT2 ANTAGONISTS | AnaMar AB (SE) | 2022-04-27 | — | — | EP | disclosed |