Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442649 | 1.00 | CHKA (0.34) | CHKAPDGFRBPDGFRAAIMP2ALDH1A1 | |
| SCHEMBL29442696 | 0.91 | CHKA (0.35) | CHKAPDGFRBPDGFRAAIMP2ALDH1A1 | |
| SCHEMBL22744560 | 0.91 | CHKA (0.35) | CHKAPDGFRBPDGFRAAIMP2ALDH1A1 | |
| SCHEMBL24650152 | 0.91 | CHKA (0.35) | CHKAPDGFRBPDGFRAAIMP2ALDH1A1 | |
| SCHEMBL29442769 | 0.91 | CHKA (0.35) | CHKAPDGFRBPDGFRAAIMP2ALDH1A1 | |
| SCHEMBL24650159 | 0.91 | CHKA (0.35) | CHKAPDGFRBPDGFRAAIMP2ALDH1A1 | |
| SCHEMBL24650178 | 0.86 | CHKA (0.35) | CHKAPDGFRBPDGFRAAIMP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29442768 | 0.85 | CHKA (0.35) | CHKAPDGFRBPDGFRAAIMP2ALDH1A1 | |
| SCHEMBL24650075 | 0.82 | NTRK1 (0.37) | CHKAPDGFRBPDGFRAALDH1A1SLC6A2 | |
| SCHEMBL29442695 | 0.82 | NTRK1 (0.37) | CHKAPDGFRBPDGFRAALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 2022-08-18 | — | — | US | disclosed |
| WO-2020241853-A1 | BENZOTRIAZOLE DERIVATIVE | 宇部興産株式会社 | 2020-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | KEAP1, NFE2L2, BACH1 | CHKA 4092/4885PDGFRB 3705/4885PDGFRA 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.