Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15670447 | 0.84 | BRD4 (0.45) | HTTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL28207370 | 0.80 | L3MBTL1 (0.47) | HTTALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL29940790 | 0.79 | ALDH1A1 (0.45) | HTTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL29476746 | 0.79 | HTT (0.45) | HTTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL28118429 | 0.79 | ALDH1A1 (0.49) | HTTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL12083380 | 0.79 | ALDH1A1 (0.45) | HTTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL29597476 | 0.79 | SMN1; SMN2 (0.51) | HTTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL8871607 | 0.79 | ALDH1A1 (0.49) | HTTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL1786991 | 0.79 | SMN1; SMN2 (0.51) | HTTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL28055380 | 0.79 | ALDH1A1 (0.45) | HTTALDH1A1POLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020238559-A1 | DE-C2-SYMMETRIC DIPHENYLAMINE-TYPE CHIRAL BISOXAZOLINE LIGAND, SYNTHESIS METHOD THEREFOR AND USE THEREOF | 浙江工业大学 | 2020-12-03 | — | — | WO | disclosed |