Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 11/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
| ▸ | BLVRB | P30043 | 1/20 | 0.63 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.63 |
| ▸ | PPID | Q08752 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22745216 | 0.82 | XDH (0.64) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL31307441 | 0.82 | XDH (0.81) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL22916848 | 0.81 | XDH (0.72) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL31217670 | 0.81 | XDH (0.72) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL22745217 | 0.81 | XDH (0.64) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL2635992 | 0.79 | XDH (0.83) | XDHABCC4ABCB11PGRCHRM1 | |
| Febuxostat SCHEMBL30161803 | 0.78 | XDH (1.00) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL16363788 | 0.78 | XDH (0.85) | XDHABCC4ABCB11PGRCHRM1 | |
| Febuxostat SCHEMBL29398803 | 0.78 | XDH (1.00) | XDHABCC4ABCB11PGRCHRM1 | |
| Febuxostat SCHEMBL28271887 | 0.78 | XDH (1.00) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3744720-A1 | THIAZOLE-5-FORMIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Xiangbei Welman Pharmaceutical Co., Ltd (CN) | 2020-12-02 | — | — | EP | disclosed |