Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21087071 | 0.78 | DAO (0.44) | PTPN1TAAR1HDAC6DAO | |
| SCHEMBL12085752 | 0.74 | KIF11 (0.37) | DAORIPK1 | |
| SCHEMBL18800289 | 0.74 | PDE2A (0.41) | TAAR1DAORIPK1 | |
| SCHEMBL18199697 | 0.74 | EPHX2 (0.38) | SLC6A4 | |
| SCHEMBL22747556 | 0.73 | PTGS1 (0.41) | PTPN1TAAR1HDAC6DAOSLC6A2 | |
| SCHEMBL11757398 | 0.73 | SLC6A4 (0.53) | PTPN1TAAR1MCL1SLC6A2SLC6A4 | |
| SCHEMBL21677385 | 0.73 | GABRA1 (0.35) | — | |
| SCHEMBL16957075 | 0.73 | KIF11 (0.36) | DAORIPK1 | |
| SCHEMBL1690346 | 0.73 | LOXL2 (0.41) | TAAR1DAO | |
| SCHEMBL13208381 | 0.73 | KIF11 (0.36) | DAORIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239124-A1 | SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2020-12-03 | — | — | WO | disclosed |