Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970739 | 0.85 | HTR6 (0.63) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL1977102 | 0.83 | HTT (0.62) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL675296 | 0.83 | HTT (0.65) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL4446725 | 0.83 | HTT (0.62) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL1970330 | 0.83 | HTR6 (0.52) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL2270543 | 0.83 | HTR6 (0.60) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL4452199 | 0.81 | HTT (0.59) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL1673252 | 0.79 | HTR6 (0.75) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL29414854 | 0.79 | HTR6 (0.75) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL3972209 | 0.79 | HTR6 (0.70) | HTR6HTTMAPTNPSR1RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998981-B2 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-08-16 | — | — | US | disclosed |
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES, LTD. (IN) | 2010-07-01 | — | — | US | disclosed |
| EP-1919896-B1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LTD (IN) | 2009-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | HTR6, HTR5A, HTR3B | HTR6 1/4885HTT 492/4885MAPT 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.