Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.75 |
| ▸ | HTT | P42858 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414854 | 1.00 | HTR6 (0.75) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL1203289 | 0.98 | HTR6 (0.73) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL429849 | 0.86 | HTR6 (1.00) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL29558135 | 0.86 | HTR6 (1.00) | HTR6HTTMEN1KMT2AALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28073916 | 0.85 | HTR6 (0.56) | HTR6HTTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28794299 | 0.84 | HTR6 (0.96) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL1898211 | 0.83 | HTR6 (0.56) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL9587047 | 0.83 | HTR6 (0.75) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL31663420 | 0.83 | HTR6 (0.81) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL1894102 | 0.83 | HTR6 (0.61) | HTR6HTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6033601-A | POLYMERIZED FROM A 1-SUBSTITUTED, 3-SUBSTITUTED OR 1,3-SUBSTITUTED INDOLE MONOMER AND A GAS SENSOR CONTAINING THIS POLYMER AS THE ACTIVE GAS SENSING ELEMENT. | AROMASCAN PLC (GB) | 2000-03-07 | — | — | US | claimed |
| US-20250382269-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | disclosed |
| CN-113880815-B | Indole derivatives, preparation method and application thereof | 中国药科大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-114133394-B | Compound selectively aiming at activity of cell cycle dependent kinase 12, preparation method and medical application | 赛诺哈勃药业（成都）有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-115353478-B | Preparation method of indole compound | 南京工业大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-111170924-B | Method for electrochemically synthesizing hexafluoroisopropoxyindole compound | 广西师范大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-115353478-A | Preparation method of indole compound | 南京工业大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-111763148-B | Alkynyl cyclopentene derivative containing trifluoromethyl and preparation method and application thereof | 广州大学 | 2022-10-28 | — | — | CN | disclosed |
| US-11479867-B2 | Electrocatalytic alkene diazidation | CORNELL UNIVERSITY (US) | 2022-10-25 | — | — | US | disclosed |
| CN-1717233-A | 4-(1-(sulfonyl)-1H-indol-2-yl)-4-(hydroxy)-cyclohexa-2,5-dienone compounds and analogs thereof as therapeutic agents | CANCER REC TECH LTD (GB) | 2006-01-04 | — | — | CN | disclosed |
| US-20050020583-A1 | Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them | PFIZER ITALIA S.R.L. (IT) | 2005-01-27 | — | — | US | disclosed |
| US-6033601-A | POLYMERIZED FROM A 1-SUBSTITUTED, 3-SUBSTITUTED OR 1,3-SUBSTITUTED INDOLE MONOMER AND A GAS SENSOR CONTAINING THIS POLYMER AS THE ACTIVE GAS SENSING ELEMENT. | AROMASCAN PLC (GB) | 2000-03-07 | — | — | US | disclosed |
| US-5679694-A | LOW TOXICITY AGAINST NORMAL CELL LINES | THE WELLCOME FOUNDATION LTD. (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0797769-A1 | SEMICONDUCTING ORGANIC POLYMERS | AROMASCAN PLC (GB) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018888-A1 | SEMICONDUCTING ORGANIC POLYMERS | AROMASCAN PLC (GB) | 1996-06-20 | — | — | WO | disclosed |
| EP-0651750-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994002483-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |
| WO-1993013079-A1 | ANTIFOLATE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | disclosed |
| CN-1056497-A | Indolone and relevant derivative with neuroprotective | PFIZER (US) | 1991-11-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382269-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CD14, MIF, NOD2 | HTR6 4706/4885HTT 3039/4885MEN1 2402/4885 |
| US-20050020583-A1 | Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them | MAP3K20, MAP3K1, MAP3K15 | HTR6 3344/4885HTT 1001/4885MEN1 1149/4885 |
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CD14, MIF, NOD2 | HTR6 4706/4885HTT 3039/4885MEN1 2402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.