Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 2/20 | 0.30 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747836 | 0.90 | EDNRA (0.36) | EDNRAMAPK8MAPK9MALT1 | |
| SCHEMBL22747877 | 0.78 | KCNH2 (0.38) | EDNRA | |
| SCHEMBL22747875 | 0.76 | EDNRA (0.36) | EDNRAMAPK8REN | |
| SCHEMBL22747879 | 0.75 | HPGD (0.42) | EDNRAMAPK8MAPK9 | |
| SCHEMBL22760496 | 0.71 | REN (0.40) | EDNRAREN | |
| SCHEMBL31444533 | 0.70 | CSNK1D (0.36) | — | |
| SCHEMBL22748355 | 0.69 | EDNRA (0.40) | EDNRARENMALT1 | |
| SCHEMBL22760177 | 0.69 | AKR1C3 (0.44) | EDNRA | |
| SCHEMBL22760062 | 0.69 | EDNRA (0.39) | EDNRAMAPK8MAPK9 | |
| SCHEMBL22760063 | 0.68 | EDNRA (0.39) | EDNRARENMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |