Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748196 | 0.90 | EDNRA (0.42) | NOTUMPIK3CAKMOKDM4EMAPT | |
| SCHEMBL22760177 | 0.90 | AKR1C3 (0.44) | KMOKDM4ECYP1A2CYP3A4HPGD | |
| SCHEMBL22748239 | 0.89 | HSD17B10 (0.41) | PRKDCPIK3CAKDM4EHPGDDDR1 | |
| SCHEMBL22747895 | 0.88 | TSHR (0.39) | NOTUMPPARGKMOKDM4ECYP1A2 | |
| SCHEMBL22748334 | 0.88 | KMO (0.40) | NOTUMKMOKDM4ECYP1A2CYP3A4 | |
| SCHEMBL22747879 | 0.86 | HPGD (0.42) | KMOKDM4ECYP1A2CYP3A4HPGD | |
| SCHEMBL22760131 | 0.86 | KMO (0.39) | KMOAKT1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL22747853 | 0.86 | MAPT (0.42) | NOTUMKMOKDM4ECYP1A2CYP3A4 | |
| SCHEMBL22748281 | 0.85 | KMO (0.37) | KMOKDM4ECYP1A2CYP3A4HPGD | |
| SCHEMBL22760212 | 0.85 | NOTUM (0.39) | NOTUMPPARGKMOKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |