Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14510509 | 0.81 | RAB9A (0.36) | RAB9AMEN1KMT2AHPGDNPC1 | |
| SCHEMBL22748469 | 0.80 | LPL (0.43) | S1PR5S1PR1MEN1KMT2AHPGD | |
| SCHEMBL13429489 | 0.79 | SMN1; SMN2 (0.39) | RAB9AMEN1KMT2AHPGDNPC1 | |
| SCHEMBL21655144 | 0.78 | LPL (0.42) | S1PR5S1PR1RAB9AMEN1KMT2A | |
| SCHEMBL19160557 | 0.77 | NR5A1 (0.50) | MEN1KMT2AHPGDTP53TSHR | |
| SCHEMBL19160763 | 0.77 | NR5A1 (0.50) | MEN1KMT2AHPGDTP53TSHR | |
| SCHEMBL19160350 | 0.77 | NR5A1 (0.50) | MEN1KMT2AHPGDTP53TSHR | |
| SCHEMBL19160349 | 0.76 | L3MBTL1 (0.46) | MEN1KMT2AHPGDTP53THRB | |
| SCHEMBL19160817 | 0.76 | L3MBTL1 (0.46) | MEN1KMT2AHPGDTP53THRB | |
| SCHEMBL19160420 | 0.76 | L3MBTL1 (0.55) | S1PR1MEN1KMT2AHPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |