Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.41 |
| ▸ | FDPS | P14324 | 9/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645383 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL22748685 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL1658760 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Ammonia Solution, Strong SCHEMBL27553300 | 0.98 | LMNA (0.48) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL1657127 | 0.97 | SMN1; SMN2 (0.48) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL31339077 | 0.90 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL1657973 | 0.90 | ALDH1A1 (0.45) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL20026795 | 0.88 | LMNA (0.62) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL1657812 | 0.87 | SMN1; SMN2 (0.63) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL20856500 | 0.87 | TSHR (0.53) | TSHRGGPS1FDPSTHRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245291-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |