Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657127 | 0.92 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL22748685 | 0.90 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL22748640 | 0.90 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL7645383 | 0.90 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL1658760 | 0.90 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL1658861 | 0.89 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| Ammonia Solution, Strong SCHEMBL27553300 | 0.87 | LMNA (0.48) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL1658296 | 0.86 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL8897968 | 0.85 | TSHR (0.43) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL588498 | 0.84 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250248975-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SCHRODINGER, LLC | 2025-08-07 | — | — | US | disclosed |
| CN-110894203-B | Organic light-emitting compound, application thereof and organic electroluminescent device | 北京绿人科技有限责任公司 | 2022-10-11 | — | — | CN | disclosed |
| EP-3191471-B1 | 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBVIE DEUTSCHLAND (DE) | 2020-03-11 | — | — | EP | disclosed |
| EP-3191471-A1 | 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-07-19 | — | — | EP | disclosed |
| US-9550754-B2 | 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-01-24 | — | — | US | disclosed |
| WO-2016038160-A1 | 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-03-17 | — | — | WO | disclosed |
| US-20160075691-A1 | 4,5- DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-03-17 | — | — | US | disclosed |
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20130131169-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8377458-B2 | Cooling sensation agent composition, sensory stimulation agent composition and use of the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110081393-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION | 2011-04-07 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| WO-2002022257-A1 | CATALYST PRECURSOR FOR PRODUCING MALEIC ACID ANHYDRIDE | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |
| US-5366657-A | Esters or ethers for electrooptical apparatus | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-22 | — | — | US | disclosed |
| EP-0513069-A1 | PROCESS FOR PRODUCING GEMINATE DIMETHYLALKYL COMPOUNDS AND THEIR USE IN LIQUID CRYSTALLINE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | disclosed |
| WO-1991011441-A1 | PROCESS FOR PRODUCING GEMINATE DIMETHYLALKYL COMPOUNDS AND THEIR USE IN LIQUID CRYSTALLINE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-08 | — | — | WO | disclosed |
| US-3979466-A | ALKALI CATALYST | CONTINENTAL OIL COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | ALDH1A1 520/4885SMN1; SMN2 2144/4885LMNA 1708/4885 |
| US-20160075691-A1 | 4,5- DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | SLC5A1, GFPT1, SULT2A1 | ALDH1A1 571/4885SMN1; SMN2 3976/4885LMNA 4550/4885 |
| US-20110081393-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TRPA1, TRPV1, TRPM4 | ALDH1A1 685/4885SMN1; SMN2 2797/4885LMNA 1727/4885 |
| US-20130131169-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TRPA1, TRPV1, TRPM4 | ALDH1A1 685/4885SMN1; SMN2 2797/4885LMNA 1727/4885 |
| US-20250248975-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | CFTR, ABCB1, PKD1 | ALDH1A1 3545/4885SMN1; SMN2 3610/4885LMNA 2396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.