Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 6/20 | 0.41 |
| ▸ | KDR | P35968 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749207 | 0.96 | CNR2 (0.47) | CNR2KDM6BKDM4CCYP1A2CYP2C19 | |
| SCHEMBL19893277 | 0.84 | CNR2 (0.47) | CNR2CYP1A2CYP2C19FLT1KDR | |
| SCHEMBL22749197 | 0.81 | ALDH1A1 (0.40) | CNR2KDM6BKDM4CCYP1A2CYP2C19 | |
| SCHEMBL30908549 | 0.75 | CNR2 (0.59) | CNR2CYP1A2CYP2C19FLT1KDR | |
| SCHEMBL1881753 | 0.75 | CNR2 (0.55) | CNR2CYP1A2CYP2C19FLT1KDR | |
| SCHEMBL27409311 | 0.73 | CNR2 (0.56) | CNR2CYP1A2CYP2C19FLT1KDR | |
| SCHEMBL22749175 | 0.72 | CNR2 (0.47) | CNR2KDM6BKDM4CKDM4ESMN1; SMN2 | |
| SCHEMBL9982691 | 0.72 | KDM4E (0.64) | CNR2KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL12723401 | 0.71 | RIPK1 (0.47) | KDM6BKDM4CCYP1A2CYP2C19KDM4E | |
| SCHEMBL2215634 | 0.71 | CNR2 (0.47) | CNR2CYP1A2CYP2C19KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12358919-B2 | Antibacterial compounds | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2025-07-15 | — | — | US | disclosed |
| US-20220235059-A1 | ANTIBACTERIAL COMPOUNDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2022-07-28 | — | — | US | disclosed |
| EP-3980418-A1 | ANTIBACTERIAL COMPOUNDS | Universita' Degli Studi di Siena (IT) | 2022-04-13 | — | — | EP | disclosed |
| WO-2020245759-A1 | ANTIBACTERIAL COMPOUNDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2020-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358919-B2 | Antibacterial compounds | ABCB11, CFTR, MRPL21 | CNR2 4529/4885KDM6B 3403/4885KDM4C 3554/4885 |
| US-20220235059-A1 | ANTIBACTERIAL COMPOUNDS | ABCB11, CFTR, MRPL21 | CNR2 4529/4885KDM6B 3403/4885KDM4C 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.