SCHEMBL2274937

SCHEMBL2274937

CCCCC([SiH3])(CCCC)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272153 0.76 LMNA (0.30) TSHRLMNA
SCHEMBL28761653 0.76 DNM1 (0.31) DNM1TSHRLMNA
SCHEMBL2267906 0.72
SCHEMBL31319809 0.71 TSHR (0.35) DNM1TSHRLMNATHRBFDPS
SCHEMBL3886534 0.69 TSHR (0.40) TSHRLMNATHRBFDPS
SCHEMBL2345610 0.69 FDPS (0.40) TSHRLMNATHRBFDPS
SCHEMBL21955613 0.69
SCHEMBL10626371 0.69 DNM1 (0.33) DNM1TSHRLMNATHRBFDPS
SCHEMBL2270120 0.69 DNM1 (0.35) DNM1
SCHEMBL8037927 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed