SCHEMBL2275372

SCHEMBL2275372

CCC(C)[SiH](C=CNC)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.31
SLC18A2 Q05940 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2267457 0.85 SIGMAR1 (0.32) SIGMAR1
SCHEMBL2271991 0.79 LMNA (0.31)
SCHEMBL2272888 0.77 RECQL (0.32)
SCHEMBL2273126 0.75
SCHEMBL15914960 0.72 LMNA (0.38) TAAR1SLC18A2SIGMAR1
SCHEMBL2272256 0.69 TAAR1 (0.35) TAAR1SLC18A2SIGMAR1
SCHEMBL2273446 0.68 SIGMAR1 (0.32) SIGMAR1
SCHEMBL15915020 0.68 LMNA (0.38) TAAR1SIGMAR1
SCHEMBL10454800 0.65 TSHR (0.38) TAAR1SIGMAR1
SCHEMBL2269772 0.65 LMNA (0.35) TAAR1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed