Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929862 | 0.84 | PIP4K2C (0.33) | KDR | |
| SCHEMBL22730040 | 0.81 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL19921135 | 0.73 | CCNK (0.50) | — | |
| SCHEMBL19929884 | 0.72 | PTK2 (0.37) | KDR | |
| SCHEMBL20546911 | 0.72 | PDE5A (0.47) | — | |
| SCHEMBL19929867 | 0.71 | PTK2 (0.36) | KDR | |
| SCHEMBL22730041 | 0.70 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL19921194 | 0.68 | ALK (0.59) | IRAK4KDRMERTK | |
| SCHEMBL19921180 | 0.68 | ALK (0.46) | — | |
| SCHEMBL19921070 | 0.68 | STAT6 (0.43) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290420-B1 | PYRIMIDINE PYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF | UNIV XIAMEN (CN) | 2020-12-09 | — | — | EP | disclosed |