Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754183 | 0.79 | AGXT (0.54) | MEN1KMT2ACYP1A2NPC1MAPT | |
| SCHEMBL1145092 | 0.79 | SLC6A4 (0.48) | SLC6A4MAOASLC6A2SLC6A3MEN1 | |
| SCHEMBL1145089 | 0.77 | SLC6A4 (0.47) | SLC6A4MAOASLC6A2SLC6A3MEN1 | |
| SCHEMBL18459027 | 0.77 | IDO1 (0.52) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL21937947 | 0.77 | IDO1 (0.52) | MEN1KMT2A | |
| SCHEMBL18459091 | 0.76 | TSHR (0.52) | MAOASLC6A2SLC6A3KMT2ACYP1A2 | |
| SCHEMBL18459071 | 0.76 | IDO1 (0.57) | SLC6A4CYP3A4NPC1RAB9A | |
| SCHEMBL20402705 | 0.76 | SLC6A4 (0.46) | SLC6A4MAOASLC6A2SLC6A3MEN1 | |
| SCHEMBL22754182 | 0.74 | ALDH1A1 (0.52) | CYP3A4NPC1MAPT | |
| SCHEMBL21343412 | 0.74 | SLC6A4 (0.52) | SLC6A4MAOASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507292-B1 | USE OF SILYLATED FORMIATES AS HYDROSILANE EQUIVALENTS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-12-09 | — | — | EP | disclosed |