Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066432 | 0.83 | AGXT (0.56) | AGXTCA1CA2CA9IDO1 | |
| SCHEMBL18459027 | 0.79 | IDO1 (0.52) | CA1CA2CA9IDO1NPC1 | |
| SCHEMBL21937947 | 0.79 | IDO1 (0.52) | AGXTCA1CA2CA9IDO1 | |
| SCHEMBL22754181 | 0.79 | SLC6A4 (0.47) | NPC1RAB9ACYP1A2MAPTMEN1 | |
| SCHEMBL18459091 | 0.78 | TSHR (0.52) | AGXTCA1CA2CA9IDO1 | |
| SCHEMBL18459071 | 0.77 | IDO1 (0.57) | AGXTCA1CA2CA9IDO1 | |
| SCHEMBL22754248 | 0.76 | APP (0.49) | CA1CA2KCNH2NPC1RAB9A | |
| SCHEMBL22754182 | 0.76 | ALDH1A1 (0.52) | CA1CA2CA9NPC1MAPT | |
| SCHEMBL2355646 | 0.75 | AGXT (0.58) | AGXTCA1CA2CA9IDO1 | |
| SCHEMBL23543614 | 0.74 | NQO1 (0.56) | CA1CA2CA9NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507292-B1 | USE OF SILYLATED FORMIATES AS HYDROSILANE EQUIVALENTS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-12-09 | — | — | EP | disclosed |