Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754183 | 0.76 | AGXT (0.54) | ALDH1A1TDP1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL7968199 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL12509337 | 0.74 | APP (0.56) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL18459027 | 0.74 | IDO1 (0.52) | ALDH1A1TDP1APPHPGDKDM4E | |
| SCHEMBL7968195 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL21937947 | 0.74 | IDO1 (0.52) | ALDH1A1APPCA1CA2CA7 | |
| SCHEMBL22754181 | 0.74 | SLC6A4 (0.47) | CYP3A4NPC1MAPT | |
| SCHEMBL24696625 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL18459091 | 0.73 | TSHR (0.52) | ALDH1A1TSHRMAPK1TDP1GAA | |
| SCHEMBL18459071 | 0.72 | IDO1 (0.57) | ALDH1A1TSHRCYP3A4APPALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507292-B1 | USE OF SILYLATED FORMIATES AS HYDROSILANE EQUIVALENTS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-12-09 | — | — | EP | disclosed |