Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754196 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL22754221 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL16979323 | 0.83 | ALDH1A1 (0.35) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL20662244 | 0.82 | CHRNB2 (0.33) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL20662273 | 0.82 | CHRNB2 (0.33) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL21207371 | 0.82 | ALDH1A1 (0.32) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL22754271 | 0.82 | CHRNB2 (0.33) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL21071251 | 0.78 | CHRNB2 (0.48) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL21070274 | 0.78 | CHRNB2 (0.48) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL28453692 | 0.78 | CHRNB2 (0.48) | ALDH1A1TP53TSHRHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099681-B1 | CYTOTOXIC TUBULYSIN COMPOUNDS AND CONJUGATES THEREOF | TUBE PHARMACEUTICALS GMBH (AT) | 2020-12-09 | — | — | EP | disclosed |