Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754887 | 0.83 | MAPT (0.40) | MGLLGAAHSD11B1 | |
| SCHEMBL22755348 | 0.82 | CNR1 (0.34) | KDM4EALDH1A1HPGDHSD17B10HSD11B1 | |
| SCHEMBL22729755 | 0.80 | MGLL (0.39) | MGLLOPRD1OPRM1KDM4EALDH1A1 | |
| SCHEMBL29839357 | 0.80 | MGLL (0.39) | MGLLOPRD1OPRM1KDM4EALDH1A1 | |
| SCHEMBL22729815 | 0.78 | ALDH1A1 (0.39) | MGLLKDM4EALDH1A1GAAHPGD | |
| SCHEMBL22729448 | 0.78 | MGLL (0.46) | MGLLKDM4EALDH1A1GAAHPGD | |
| SCHEMBL22755127 | 0.78 | MGLL (0.41) | MGLLOPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL22755345 | 0.78 | ALDH1A1 (0.33) | MGLLOPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL22755139 | 0.78 | MGLL (0.39) | MGLLKDM4EALDH1A1GAAHPGD | |
| SCHEMBL22729433 | 0.77 | ALDH1A1 (0.38) | MGLLOPRD1OPRK1SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |