Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 4/20 | 0.33 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755266 | 0.86 | MGLL (0.41) | MGLLALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL22729763 | 0.86 | ALDH1A1 (0.40) | MGLLALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL22755344 | 0.84 | MGLL (0.47) | MGLLSPRHSD11B1 | |
| SCHEMBL22755140 | 0.84 | MGLL (0.42) | MGLLALDH1A1HPGDSPRHTT | |
| SCHEMBL22755287 | 0.82 | MGLL (0.38) | MGLLHSD11B1 | |
| SCHEMBL22754903 | 0.81 | MGLL (0.37) | MGLLALDH1A1HPGDLMNAMAPT | |
| SCHEMBL22754986 | 0.81 | MGLL (0.37) | MGLLHSD17B10MAPK1HSD11B1 | |
| SCHEMBL22755032 | 0.80 | MGLL (0.40) | MGLLALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL22755031 | 0.80 | MGLL (0.35) | MGLLHSD11B1 | |
| SCHEMBL22755295 | 0.78 | MGLL (0.35) | MGLLALDH1A1HPGDMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |