Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 6/20 | 0.34 |
| ▸ | PDE2A | O00408 | 5/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729586 | 0.88 | DRD2 (0.37) | DRD2DRD3KCNH2MGLLPDE2A | |
| SCHEMBL22754870 | 0.84 | MGLL (0.40) | MGLL | |
| SCHEMBL22755297 | 0.83 | SLC6A2 (0.37) | MGLL | |
| SCHEMBL22754971 | 0.83 | MGLL (0.40) | DRD2MGLL | |
| SCHEMBL22755125 | 0.82 | MGLL (0.40) | MGLL | |
| SCHEMBL29839330 | 0.78 | GRIN2B (0.36) | MGLL | |
| SCHEMBL22729757 | 0.78 | GRIN2B (0.36) | MGLL | |
| SCHEMBL22729525 | 0.77 | MGLL (0.36) | MGLLPDE2AHCRTR1HCRTR2SLC6A9 | |
| SCHEMBL22755073 | 0.77 | PDE2A (0.37) | MGLLPDE2AHCRTR1HCRTR2SLC6A9 | |
| SCHEMBL22754886 | 0.77 | MGLL (0.37) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |