Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755304 | 0.87 | MGLL (0.40) | MGLL | |
| SCHEMBL22729457 | 0.87 | TSHR (0.39) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL29839371 | 0.87 | TSHR (0.39) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22755326 | 0.86 | MGLL (0.34) | MGLLP2RX7 | |
| SCHEMBL22754903 | 0.86 | MGLL (0.37) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22755295 | 0.86 | MGLL (0.35) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22755344 | 0.83 | MGLL (0.47) | MGLL | |
| SCHEMBL22755031 | 0.83 | MGLL (0.35) | MGLL | |
| SCHEMBL22754902 | 0.81 | SLC6A2 (0.36) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL22755287 | 0.81 | MGLL (0.38) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |