Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | SPR | P35270 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755031 | 0.88 | MGLL (0.35) | MGLLHSD11B1 | |
| SCHEMBL22729600 | 0.87 | ALDH1A1 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1HSD17B10 | |
| SCHEMBL29839324 | 0.87 | ALDH1A1 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1HSD17B10 | |
| SCHEMBL22755326 | 0.86 | MGLL (0.34) | MGLL | |
| SCHEMBL22755282 | 0.86 | DRD3 (0.34) | MGLLMAPTHSD11B1SPR | |
| SCHEMBL22754885 | 0.84 | HCRTR1 (0.35) | MGLLHSD11B1SPRHCRTR1HCRTR2 | |
| SCHEMBL22755344 | 0.83 | MGLL (0.47) | SLC6A2SLC6A4SLC6A3MGLLHSD11B1 | |
| SCHEMBL22755287 | 0.83 | MGLL (0.38) | MGLLHSD11B1MEN1KMT2A | |
| SCHEMBL22755016 | 0.81 | TSHR (0.34) | ALDH1A1MGLLNPSR1MAPTLMNA | |
| SCHEMBL22754903 | 0.81 | MGLL (0.37) | ALDH1A1MGLLNPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |