Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755233 | 0.92 | MGLL (0.33) | MGLL | |
| SCHEMBL22754903 | 0.91 | MGLL (0.37) | MGLLALDH1A1MAPTHPGDTSHR | |
| SCHEMBL22755304 | 0.89 | MGLL (0.40) | MGLL | |
| SCHEMBL22755344 | 0.88 | MGLL (0.47) | MGLLSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22755016 | 0.86 | TSHR (0.34) | MGLLALDH1A1MAPTHPGDTSHR | |
| SCHEMBL22729774 | 0.86 | ALDH1A1 (0.35) | MGLLSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL22755287 | 0.86 | MGLL (0.38) | MGLL | |
| SCHEMBL22755286 | 0.85 | MGLL (0.36) | MGLLSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL22754986 | 0.84 | MGLL (0.37) | MGLL | |
| SCHEMBL22755032 | 0.84 | MGLL (0.40) | MGLLSLC6A2SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |