Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.38 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.38 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.38 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.38 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20900619 | 0.90 | PLG (0.51) | L3MBTL1PLGGCGRKIFC1RARB | |
| SCHEMBL16306221 | 0.90 | GCGR (0.53) | L3MBTL1PLGGCGRCTSBCTSS | |
| SCHEMBL16305379 | 0.89 | GCGR (0.52) | L3MBTL1PLGGCGRCTSBCTSS | |
| SCHEMBL16305376 | 0.89 | GCGR (0.52) | L3MBTL1PLGGCGRCTSBCTSS | |
| SCHEMBL16305835 | 0.89 | GCGR (0.52) | L3MBTL1PLGGCGRCTSBCTSS | |
| SCHEMBL16305377 | 0.87 | GCGR (0.53) | L3MBTL1PLGGCGRCTSBCTSS | |
| SCHEMBL20900666 | 0.86 | PLG (0.48) | L3MBTL1PLGCTSBCTSSCTSK | |
| SCHEMBL16306222 | 0.85 | L3MBTL1 (0.46) | L3MBTL1PLGGCGRCTSBCTSS | |
| SCHEMBL19485581 | 0.85 | KIFC1 (0.46) | L3MBTL1PLGGCGRKIFC1 | |
| SCHEMBL17968973 | 0.84 | L3MBTL1 (0.44) | L3MBTL1PLGGCGRCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |