SCHEMBL22757006

SCHEMBL22757006

c1cc(-c2ccccc2N(c2ccc(-c3cccc4ccccc34)cc2)c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc(-c2cccc3ccccc23)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.50
▸ GGPS1 O95749 1/20 0.41
▸ PRKDC P78527 5/20 0.39
▸ PTGES2 Q9H7Z7 1/20 0.39
▸ CA12 O43570 2/20 0.36
▸ CA1 P00915 2/20 0.36
▸ CA2 P00918 2/20 0.36
▸ CA9 Q16790 2/20 0.36
▸ PRMT5 O14744 1/20 0.34
▸ WDR77 Q9BQA1 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ MCL1 Q07820 1/20 0.34
▸ ACMSD Q8TDX5 1/20 0.34
▸ ENPP3 O14638 1/20 0.34
▸ ENPP1 P22413 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18655611 1.00 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL23238374 1.00 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL23238322 0.98 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL18655607 0.98 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL23056829 0.98 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL23237063 0.98 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL23237952 0.98 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL23238633 0.97 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL23238497 0.97 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2CA12
SCHEMBL23239468 0.97 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730054-B2 Compound having dibenzofuran and naphthalene structures, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-11730054-B2 Compound having dibenzofuran and naphthalene structures, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-20230047512-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 — — US disclosed
US-20210066611-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO,. LTD. (JP) 2021-03-04 — — US disclosed
EP-3747876-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co.,Ltd. (JP) 2020-12-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210066611-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME LEF1, RPL19, ELP1 ALOX5 861/4885GGPS1 2674/4885PRKDC 4875/4885
US-11730054-B2 Compound having dibenzofuran and naphthalene structures, and organic electroluminescent element using same LEF1, TCF4, RPL19 ALOX5 713/4885GGPS1 2567/4885PRKDC 4844/4885
US-20230047512-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME LEF1, RPL19, ELP1 ALOX5 861/4885GGPS1 2674/4885PRKDC 4875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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