SCHEMBL22758089

SCHEMBL22758089

NC(=O)C(c1ccc(F)cc1)C1CC1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CACNA1B Q00975 2/20 0.42
DPP4 P27487 2/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
CYP2D6 P10635 1/20 0.39
KCNH2 Q12809 1/20 0.39
DPP8 Q6V1X1 1/20 0.39
DPP9 Q86TI2 1/20 0.39
DPP7 Q9UHL4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29926647 0.91 DPP4 (0.45) CACNA1BDPP4KCNH2DPP8DPP9
SCHEMBL29277467 0.89 SLC6A2 (0.46)
SCHEMBL14410194 0.85 HRH3 (0.44) CACNA1BDPP4KCNH2DPP8DPP9
SCHEMBL7268591 0.83 CACNA1B (0.43) CACNA1BHDAC3HDAC4HDAC1HDAC7
SCHEMBL22188704 0.81 HTR1E (0.51)
SCHEMBL4176732 0.81 HTR1E (0.51)
SCHEMBL25326881 0.78 MMP13 (0.53) DPP4
SCHEMBL1570220 0.78 HTR1E (0.35)
SCHEMBL1565063 0.76 HTR1E (0.47) CACNA1BHDAC6
SCHEMBL16054517 0.76 SLC6A3 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020244968-A1 FUNGICIDAL N-(PYRID-3-YL)CARBOXAMIDES BASF SE (DE) 2020-12-10 WO disclosed