Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547970 | 1.00 | DGKA (0.52) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL8904237 | 1.00 | DGKA (0.52) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL22734506 | 1.00 | DGKA (0.52) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL22734492 | 1.00 | DGKA (0.52) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL20547969 | 1.00 | DGKA (0.52) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL21984344 | 1.00 | DGKA (0.52) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL22734507 | 1.00 | DGKA (0.52) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL22734505 | 1.00 | DGKA (0.52) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL22734495 | 0.96 | ALDH1A1 (0.56) | DGKAALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL22734496 | 0.96 | ALDH1A1 (0.56) | DGKAALDH1A1CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407726-B2 | Using stereoretention for the stereoselective formation of e-macrocycles with Ru-based olefin metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-08-09 | — | — | US | disclosed |
| US-20200385360-A1 | USING STEREORETENTION FOR THE STEREOSELECTIVE FORMATION OF E-MACROCYCLES WITH RU-BASED OLEFIN METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385360-A1 | USING STEREORETENTION FOR THE STEREOSELECTIVE FORMATION OF E-MACROCYCLES WITH RU-BASED OLEFIN METATHESIS CATALYSTS | OXER1, SPR, DHCR7 | DGKA 3890/4885ALDH1A1 1159/4885CYP3A4 81/4885 |
| US-11407726-B2 | Using stereoretention for the stereoselective formation of e-macrocycles with Ru-based olefin metathesis catalysts | OXER1, SPR, DHCR7 | DGKA 3890/4885ALDH1A1 1159/4885CYP3A4 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.