SCHEMBL22760055

SCHEMBL22760055

CC(C)(C)CC(C)(C)c1ccc(OC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c(C2C(=O)Oc3ccc(C(C)(C)CC(C)(C)C)cc32)c1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDH1 P40925 4/20 0.31
MDH2 P40926 4/20 0.31
LMNA P02545 1/20 0.30
RECQL P46063 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29815170 0.90 MAPT (0.36) MEN1MAPTKMT2A
SCHEMBL29876492 0.90 MAPT (0.36) MEN1MAPTKMT2A
SCHEMBL12273588 0.90 MAPT (0.36) MEN1MAPTKMT2A
SCHEMBL466198 0.84 GAA (0.34) MDH1MDH2LMNAMAPT
SCHEMBL21596649 0.84 MAPT (0.35) MEN1MAPTKMT2A
SCHEMBL12456274 0.82 MAPT (0.38) MEN1MAPTKMT2A
SCHEMBL22068545 0.79 MAPT (0.40) MDH1MDH2RECQLMEN1MAPT
SCHEMBL28498057 0.78 ALDH1A1 (0.31) MAPT
SCHEMBL13726769 0.77 ALDH1A1 (0.33) MDH1MDH2MAPT
SCHEMBL30172495 0.77 ALDH1A1 (0.33) MDH1MDH2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200385570-A1 POLYCARBONATE COMPOSITIONS BASF SE (DE) 2020-12-10 US disclosed