SCHEMBL466198

SCHEMBL466198

CC(=O)Oc1ccc(C(C)(C)CC(C)(C)C)cc1C1C(=O)Oc2ccc(C(C)(C)CC(C)(C)C)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
CYP3A4 P08684 4/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SHBG P04278 1/20 0.33
MAPT P10636 1/20 0.32
GAPDH P04406 1/20 0.32
USP2 O75604 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
NR3C1 P04150 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP2C19 P33261 1/20 0.32
MDH1 P40925 2/20 0.31
MDH2 P40926 2/20 0.31
LMNA P02545 1/20 0.31
INSR P06213 1/20 0.31
IGF1R P08069 1/20 0.31
TMEM97 Q5BJF2 1/20 0.31
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30172495 0.92 ALDH1A1 (0.33) GAACYP3A4SMN1; SMN2SHBGMAPT
SCHEMBL13726769 0.92 ALDH1A1 (0.33) GAACYP3A4SMN1; SMN2SHBGMAPT
SCHEMBL12345424 0.90 ALDH1A1 (0.32) GAASMN1; SMN2MAPTUSP2HSD17B10
SCHEMBL17454872 0.90 ALDH1A1 (0.38) GAACYP3A4SMN1; SMN2MAPTUSP2
SCHEMBL22068545 0.87 MAPT (0.40) GAACYP3A4SMN1; SMN2SHBGMAPT
SCHEMBL23071652 0.85 GAA (0.34) GAACYP3A4SMN1; SMN2SHBGMAPT
SCHEMBL18590074 0.85 GAA (0.34) GAACYP3A4SMN1; SMN2SHBGMAPT
SCHEMBL13652868 0.84 GABBR2 (0.33)
SCHEMBL22760055 0.84 MDH1 (0.31) MAPTMDH1MDH2LMNA
SCHEMBL22068557 0.84 GAA (0.34) GAACYP3A4SMN1; SMN2SHBGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115038748-B Composition and method for producing the same 瑞士新集团股份有限公司 2024-04-12 CN disclosed
EP-4249551-A2 COMPOSITION SI Group-Switzerland GmbH (CH) 2023-09-27 EP disclosed
US-11713386-B2 Composition SI GROUP, INC. (US) 2023-08-01 US disclosed
US-11713386-B2 Composition SI GROUP, INC. (US) 2023-08-01 US disclosed
US-20230055301-A1 Stabilizer Composition SI GROUP, INC. 2023-02-23 US disclosed
EP-4081584-A1 STABILIZER COMPOSITION SI Group Switzerland (CHAA) GmbH (CH) 2022-11-02 EP disclosed
CN-115038748-A Composition comprising a metal oxide and a metal oxide 瑞士新集团股份有限公司 2022-09-09 CN disclosed
US-20220033619-A1 COMPOSITION SI GROUP, INC. 2022-02-03 US disclosed
US-20220033620-A1 COMPOSITION SI GROUP, INC. 2022-02-03 US disclosed
US-11180631-B2 Antioxidant composition SI GROUP USA (USAA), LLC (US) 2021-11-23 US disclosed
US-20080122128-A1 Method for producing optical film KONICA MINOLTA OPTO, INC. (JP) 2008-05-29 US disclosed
US-20080122128-A1 Method for producing optical film KONICA MINOLTA OPTO, INC. (JP) 2008-05-29 US disclosed
WO-2008043853-A2 PHOTOCHROMIC FILM OPCO GMBH (DE) 2008-04-17 WO disclosed
WO-2008043848-A2 PROTECTIVE FILM OPCO GMBH (DE) 2008-04-17 WO disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed
US-20070185250-A1 Stabilization of polyether polyols, polyester polyols and polyurethanes CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-08-09 US disclosed
US-20070185250-A1 Stabilization of polyether polyols, polyester polyols and polyurethanes CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185250-A1 Stabilization of polyether polyols, polyester polyols and polyurethanes PUF60, UFL1, XRCC5 GAA 1121/4885CYP3A4 1701/4885SMN1; SMN2 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.