Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760416 | 0.92 | EDNRA (0.41) | EDNRANOTUMKMT2AGAAMAPT | |
| SCHEMBL22747827 | 0.88 | SMN1; SMN2 (0.42) | NOTUMKMT2AGAANPC1RAB9A | |
| SCHEMBL22760060 | 0.87 | NOTUM (0.40) | NOTUMKMT2AGAAMAPTNPC1 | |
| SCHEMBL22747915 | 0.87 | ALDH1A1 (0.40) | EDNRAKMT2AGAAMAPTRAB9A | |
| SCHEMBL22760336 | 0.84 | MAPK8 (0.41) | KMT2AGAAMAPTNPC1RAB9A | |
| SCHEMBL22747824 | 0.84 | EDNRA (0.40) | EDNRANOTUMKMT2AGAAMAPT | |
| SCHEMBL22747903 | 0.83 | RAB9A (0.38) | KMT2AGAAMAPTNPC1RAB9A | |
| SCHEMBL22760396 | 0.82 | MAPT (0.35) | KMT2AGAAMAPTNPC1RAB9A | |
| SCHEMBL22760133 | 0.82 | MAPK8 (0.46) | MAPK8 | |
| SCHEMBL22760058 | 0.81 | ALDH1A1 (0.39) | NOTUMKMT2AGAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |