Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 20/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747915 | 0.87 | ALDH1A1 (0.40) | MAPK8 | |
| SCHEMBL22747862 | 0.84 | MAPK8 (0.41) | MAPK8MAPK9MAPK10 | |
| SCHEMBL22760336 | 0.83 | MAPK8 (0.41) | MAPK8 | |
| SCHEMBL22760056 | 0.82 | EDNRA (0.41) | MAPK8 | |
| SCHEMBL22760335 | 0.81 | MAPK8 (0.41) | MAPK8MAPK9MAPK10 | |
| SCHEMBL22747827 | 0.80 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL22760058 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL22760060 | 0.79 | NOTUM (0.40) | — | |
| SCHEMBL22760357 | 0.79 | REN (0.38) | MAPK8 | |
| SCHEMBL22760046 | 0.79 | REN (0.38) | MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |