Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 2/20 | 0.38 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747888 | 0.86 | FOLH1 (0.42) | FOLH1GAAGFERSMN1; SMN2EDNRA | |
| SCHEMBL22760442 | 0.85 | EDNRA (0.50) | FOLH1GAAGFEREDNRAMAPK8 | |
| SCHEMBL22760471 | 0.85 | FOLH1 (0.44) | FOLH1GAAGFERSMN1; SMN2EDNRA | |
| SCHEMBL9538849 | 0.83 | KDM4E (0.57) | FOLH1SMN1; SMN2EDNRAMEN1KMT2A | |
| SCHEMBL22760121 | 0.82 | FOLH1 (0.39) | FOLH1GAASMN1; SMN2MAPK8MAPK9 | |
| SCHEMBL22747870 | 0.82 | FOLH1 (0.42) | FOLH1EDNRAMAPK8MAPK9 | |
| SCHEMBL22747914 | 0.82 | MAPK8 (0.40) | FOLH1EDNRAMAPK8MAPK9 | |
| SCHEMBL22760346 | 0.81 | FOLH1 (0.45) | FOLH1GAAEDNRAMAPK8MAPK9 | |
| SCHEMBL22760073 | 0.81 | CENPE (0.39) | FOLH1SMN1; SMN2MAPK8MEN1KMT2A | |
| SCHEMBL22748249 | 0.78 | FOLH1 (0.39) | FOLH1GAAGFERSMN1; SMN2EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |