Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760215 | 0.93 | HPGD (0.51) | HPGDMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL22760192 | 0.91 | ALDH1A1 (0.41) | HPGDMAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL22760342 | 0.91 | HPGD (0.45) | HPGDMAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL22747825 | 0.91 | HPGD (0.45) | HPGDMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL22760115 | 0.89 | MAPT (0.46) | HPGDMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL22760126 | 0.88 | EDNRA (0.41) | HPGDMAPTALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL22760214 | 0.84 | MAPT (0.42) | HPGDMAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL22760185 | 0.84 | HPGD (0.43) | HPGDMAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL22748239 | 0.84 | HSD17B10 (0.41) | HPGDALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL22747885 | 0.83 | HPGD (0.45) | HPGDMAPTALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |