Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 6/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760974 | 0.97 | TGFBR1 (0.38) | TGFBR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22761000 | 0.92 | TGFBR1 (0.38) | TGFBR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21546513 | 0.89 | CHEK1 (0.38) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL22760969 | 0.89 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL22760699 | 0.88 | CHEK1 (0.38) | ALDH1A3CLK4ALDH1A1CYP1A2ADORA2A | |
| SCHEMBL22822586 | 0.88 | TGFBR1 (0.35) | TGFBR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22760998 | 0.87 | ALDH1A3 (0.40) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL22760645 | 0.87 | PDK2 (0.38) | TGFBR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22761073 | 0.86 | GABRG2 (0.44) | TGFBR1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21546966 | 0.86 | CHEK1 (0.36) | GABRG2GABRB3GABRA5GABRA3GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981930-B2 | Organic molecules for use in optoelectronic devices | CYNORA GMBH (DE) | 2021-04-20 | — | — | US | disclosed |
| US-20200385399-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981930-B2 | Organic molecules for use in optoelectronic devices | OR10J3, OR51E2, EPCAM | TGFBR1 2580/4885GABRG2 1767/4885GABRB3 1915/4885 |
| US-20200385399-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | OR10J3, OR51E2, EPCAM | TGFBR1 2580/4885GABRG2 1767/4885GABRB3 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.