Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31554497 | 0.84 | DGAT1 (0.38) | DGAT1NPC1MAPTBRD4CREBBP | |
| SCHEMBL22761903 | 0.80 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL22748699 | 0.79 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL14697498 | 0.77 | DGAT1 (0.33) | DGAT1NPC1MAPTF2RL1 | |
| SCHEMBL22761905 | 0.76 | — | — | |
| SCHEMBL29562226 | 0.76 | P2RX3 (0.44) | — | |
| SCHEMBL16977995 | 0.75 | DGAT1 (0.38) | DGAT1NPC1MAPTBRD4CREBBP | |
| SCHEMBL2112213 | 0.75 | DGAT1 (0.43) | DGAT1NPC1MAPTBRD4CREBBP | |
| SCHEMBL23022191 | 0.75 | DGAT1 (0.34) | DGAT1NPC1MAPTBRD4CREBBP | |
| SCHEMBL29507119 | 0.75 | DGAT1 (0.34) | DGAT1NPC1MAPTBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244607-A1 | P2X3 AND/OR P2X2/3 RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 北京泰德制药股份有限公司 | 2020-12-10 | — | — | WO | disclosed |